DFF45 (Cleaved-Ser118) rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-00038

50UL $180 100UL $255
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Product introduction Experimental scheme Citation Related products

Product introduction>

Host

Reactiveness

Use

Molecular weight (DA)

24 36kD

Immunogen

Synthesized peptide derived from human DFF45 (Cleaved-Ser118)

Specificity

This antibody detects endogenous levels of Human DFF45 (Cleaved-Ser118, protein was cleaved amino acid sequence between117-118 )

Source

Polyclonal, Rabbit,IgG

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Dilution rate

WB 1:1000-2000 ELISA 1:5000-20000

Purification process (Immunogen)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Background

function:Inhibitor of the caspase-activated DNase (DFF40).,PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CIDE-N domain.,subunit:Heterodimer of DFFA and DFFB.,

Function

DNA catabolic process, endonucleolytic, DNA metabolic process, DNA catabolic process, DNA fragmentation involved in apoptosis, apoptosis, induction of apoptosis, cell structure disassembly during apoptosis, nucleus organization,intracellular signaling cascade, cell death, macromolecule catabolic process, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, cellular component disassembly,apoptotic nuclear changes, regulation of apoptosis, positive regulation of apoptosis, negative regulation of apoptosis,regulation of programmed cell death, positive regulation of programmed cell death, negative regulation of programmed cell death, cellular macromolecule catabolic process, negative regulation of cell death,

Gene Name

DFFA DFF1 DFF45 H13

Protein name

DFF45 (Cleaved-Ser118)

Abbreviation

DFF45

Other name

DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit;DFF-45;Inhibitor of CAD;ICAD)

DFF45 (Cleaved-Ser118) rabbit pAb

BYab-00038

Product introduction>

Host

Reactiveness

Use

Molecular weight (DA)

Immunogen

Specificity

Source

Formulation

Dilution rate

Purification process (Immunogen)

Concentration

Background

Function

Gene Name

Protein name

Abbreviation

Other name

Fields

Human gene ID

Human protein sequence Database

Mouse gene ID

Mouse protein sequence database

Rat gene ID

Rat protein sequence database

Cellular localization

Tissue expression

Storage

Experimental scheme>

Citation>

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DFF45 (Cleaved-Ser118) rabbit pAb

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