Immunogen
Purified recombinant fragment of human PEA3 (aa50-109) expressed in E. Coli.
Specificity
PEA3 Monoclonal Antibody detects endogenous levels of PEA3 protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
Affinity purification
Background
function:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,
Function
function:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,
Protein name
ETS translocation variant 4
Other name
ETV4; E1AF; PEA3; ETS translocation variant 4; Adenovirus E1A enhancer-binding protein; E1A-F; Polyomavirus enhancer activator 3 homolog; Protein PEA3
Fields
>>Transcriptional misregulation in cancer
Human protein sequence Database
P43268
Mouse protein sequence database
P28322
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in keratinocytes.