Molecular weight (DA)
130kD
Immunogen
Purified recombinant human DBC1 protein fragments expressed in E.coli
Specificity
This antibody detects endogenous levels of DBC1 and does not cross-react with related proteins
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
wb 1:500 icc 1:200
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Background
tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
Function
tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
Other name
DBCCR1;Deleted in bladder cancer protein 1;Deleted in bladder cancer protein 1 recursor; FAM5A;Protein FAM5A.
Human protein sequence Database
Q8N163
Mouse protein sequence database
Q8VDP4
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Recruited to chromatin, post-UV irradiation. Sequestered to the cytoplasm in the presence of MCC. Translocated to the cytoplasm during UV-induced apoptosis. .
Tissue expression
Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.
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