Immunogen
The antiserum was produced against synthesized peptide derived from human AGR3. AA range:1-50
Specificity
AGR3 Polyclonal Antibody detects endogenous levels of AGR3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the AGR family.,subunit:Interacts with LYPD3 and alpha-dystroglycan.,
Function
similarity:Belongs to the AGR family.,subunit:Interacts with LYPD3 and alpha-dystroglycan.,
Protein name
Anterior gradient protein 3 homolog
Other name
AGR3; BCMP11; Anterior gradient protein 3 homolog; AG-3; AG3; hAG-3; Breast cancer membrane protein 11
Human protein sequence Database
Q8TD06
Mouse protein sequence database
Q8R3W7
Rat protein sequence database
Cellular localization
Endoplasmic reticulum . Found in the cytoplasm, which could include the endoplasmic reticulum. .
Tissue expression
Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668). Expression increased with differentiation of airway epithelial cells (PubMed:25751668). Not detected in the mucous cells (PubMed:25751668). Expressed in ciliated cells in the oviduct (PubMed:26170690). Also detected in stomach, colon, prostate and liver (PubMed:25751668). Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690). Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690).
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