Molecular weight (DA)
36kD
Immunogen
The antiserum was produced against synthesized peptide derived from human BNIP2. AA range:265-314
Specificity
BNIP-2 Polyclonal Antibody detects endogenous levels of BNIP-2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Function
function:Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.,similarity:Contains 1 CRAL-TRIO domain.,subcellular location:Localizes to the nuclear envelope region and to other cytoplasmic structures.,
Protein name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Other name
BNIP2; NIP2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Human protein sequence Database
Q12982
Mouse protein sequence database
O54940
Rat protein sequence database
Cellular localization
Cytoplasm. Cytoplasm, perinuclear region. Localizes to the nuclear envelope region and to other cytoplasmic structures.
Tissue expression
Eye,Platelet,
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