Molecular weight (DA)
22kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TPD54. AA range:141-190
Specificity
D54 Polyclonal Antibody detects endogenous levels of D54 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011],
Function
alternative products:Additional isoforms seem to exist,similarity:Belongs to the TPD52 family.,subunit:Forms homodimer or heterodimer with other members of the family (By similarity). Interacts with MAL2.,
Protein name
Tumor protein D54
Other name
TPD52L2; Tumor protein D54; hD54; Tumor protein D52-like 2
Human protein sequence Database
O43399
Mouse protein sequence database
Q9CYZ2
Rat protein sequence database
Q6PCT3
Cellular localization
cytoplasm,perinuclear region of cytoplasm,
Tissue expression
Cord blood,Endometrium,Epithelium,Mammary gland,Placenta,Thyroid,Tongue,