Molecular weight (DA)
81kD
Immunogen
The antiserum was produced against synthesized peptide derived from human FAKD2. AA range:171-220
Specificity
FASTKD2 Polyclonal Antibody detects endogenous levels of FASTKD2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that is localized in the mitochondrial inner compartment and that may play a role in mitochondrial apoptosis. Nonsense mutations have been reported to result in cytochrome c oxidase deficiency. [provided by RefSeq, Oct 2008],
Function
caution:It is uncertain whether Met-1 or Met-17 is the initiator.,similarity:Belongs to the FAST kinase family.,similarity:Contains 1 RAP domain.,
Protein name
FAST kinase domain-containing protein 2
Other name
FASTKD2; KIAA0971; FAST kinase domain-containing protein 2
Human protein sequence Database
Q9NYY8
Mouse protein sequence database
Q922E6
Rat protein sequence database
Cellular localization
Mitochondrion matrix, mitochondrion nucleoid . Mitochondrion matrix . Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. .
Tissue expression
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid.
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