Molecular weight (DA)
36kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GAS1. AA range:241-290
Specificity
Gas1 Polyclonal Antibody detects endogenous levels of Gas1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008],
Function
function:Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.,
Protein name
Growth arrest-specific protein 1
Other name
GAS1; Growth arrest-specific protein 1; GAS-1
Fields
>>Hedgehog signaling pathway
Human protein sequence Database
P54826
Mouse protein sequence database
Q01721
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor .
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