Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GSDMC. AA range:109-158
Specificity
Gasdermin C Polyclonal Antibody detects endogenous levels of Gasdermin C protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
Function
caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
Other name
GSDMC; MLZE; Gasdermin-C; Melanoma-derived leucine zipper-containing extranuclear factor
Human protein sequence Database
Q9BYG8
Mouse protein sequence database
Q99NB5
Rat protein sequence database
Cellular localization
[Gasdermin-C]: Cytoplasm, cytosol .; [Gasdermin-C, N-terminal]: Cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310).
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