Molecular weight (DA)
78kD
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human MUM1. AA range:661-710
Specificity
MUM1 Polyclonal Antibody detects endogenous levels of MUM1
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MUM1 family.,
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MUM1 family.,
Other name
melanoma associated antigen (mutated) 1
Human protein sequence Database
Q2TAK8
Mouse protein sequence database
Q6DID5
Rat protein sequence database
B1H224
Cellular localization
Nucleus . Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
Tissue expression
Brain,Melanoma,Placenta,PNS,Thyroid,