Immunogen
Purified recombinant fragment of ApoM expressed in E. Coli.
Specificity
ApoM Monoclonal Antibody detects endogenous levels of ApoM protein.
Formulation
Purified antibody in PBS containing 0.03% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
Affinity purification
Background
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012],
Function
function:Probably involved in lipid transport.,similarity:Belongs to the calycin superfamily. Lipocalin family. Highly divergent.,subcellular location:Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL).,tissue specificity:Plasma protein. Expressed in liver and kidney.,
Protein name
Apolipoprotein M
Other name
APOM; G3A; NG20; HSPC336; Apolipoprotein M; Apo-M; ApoM; Protein G3a
Human protein sequence Database
O95445
Mouse protein sequence database
Q9Z1R3
Rat protein sequence database
Cellular localization
Secreted . Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL).
Tissue expression
Plasma protein. Expressed in liver and kidney.