Immunogen
Purified recombinant fragment of NPT1 expressed in E. Coli.
Specificity
NPT1 Monoclonal Antibody detects endogenous levels of NPT1 protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
Affinity purification
Background
caution:It is uncertain whether Met-1 or Met-3 is the initiator.,function:Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.,subunit:Interacts with PDZK1.,tissue specificity:Expressed in kidney cortex, liver and brain but not in other tissues.,
Function
caution:It is uncertain whether Met-1 or Met-3 is the initiator.,function:Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.,subunit:Interacts with PDZK1.,tissue specificity:Expressed in kidney cortex, liver and brain but not in other tissues.,
Protein name
Sodium-dependent phosphate transport protein 1
Other name
SLC17A1; NPT1; Sodium-dependent phosphate transport protein 1; Na(+)/PI cotransporter 1; Na/Pi-4; Renal Na(+)-dependent phosphate cotransporter 1; Renal sodium-dependent phosphate transport protein 1; Renal sodium-phosphate transport protei
Human protein sequence Database
Q14916
Mouse protein sequence database
Q61983
Rat protein sequence database
Cellular localization
Apical cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed in kidney cortex, liver and brain but not in other tissues.
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