Molecular weight (DA)
34kD
Immunogen
The antiserum was produced against synthesized peptide derived from human APOL4. AA range:301-350
Specificity
ApoL4 Polyclonal Antibody detects endogenous levels of ApoL4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the apolipoprotein L family and may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Two transcript variants encoding two different isoforms have been found for this gene. Only one of the isoforms appears to be a secreted protein. [provided by RefSeq, Jul 2008],
Function
function:May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.,similarity:Belongs to the apolipoprotein L family.,tissue specificity:Widely expressed; the highest levels are in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis; levels are low in brain, heart and pancreas.,
Protein name
Apolipoprotein L4
Other name
APOL4; Apolipoprotein L4; Apolipoprotein L-IV; ApoL-IV
Human protein sequence Database
Q9BPW4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Widely expressed; the highest levels are in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis; levels are low in brain, heart and pancreas.
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