Molecular weight (DA)
82kD
Immunogen
Synthesized peptide derived from the Internal region of human MxB.
Specificity
MxB Polyclonal Antibody detects endogenous levels of MxB protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008],
Function
induction:By interferons.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,
Protein name
Interferon-induced GTP-binding protein Mx2
Other name
MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
Fields
>>Viral life cycle - HIV-1;>>Hepatitis C;>>Measles;>>Influenza A;>>Human papillomavirus infection;>>Coronavirus disease - COVID-19
Human protein sequence Database
P20592
Mouse protein sequence database
Q9WVP9
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Nucleus, nuclear pore complex . Localization to nuclear pores requires GTP-binding.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车