Molecular weight (DA)
140kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NUP160. AA range:392-441
Specificity
Nup160 Polyclonal Antibody detects endogenous levels of Nup160 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
nucleoporin 160(NUP160) Homo sapiens NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004],
Function
caution:It is uncertain whether Met-1 or Met-35 is the initiator.,function:Involved in poly(A)+ RNA transport.,sequence caution:Probable cloning artifact. Aberrant splice sites.,subunit:Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus.,
Protein name
Nuclear pore complex protein Nup160
Other name
NUP160; KIAA0197; NUP120; Nuclear pore complex protein Nup160; 160 kDa nucleoporin; Nucleoporin Nup160
Fields
>>Nucleocytoplasmic transport;>>Amyotrophic lateral sclerosis
Human protein sequence Database
Q12769
Mouse protein sequence database
Q9Z0W3
Rat protein sequence database
Cellular localization
Nucleus, nuclear pore complex .
Tissue expression
Bone marrow,Epithelium,Muscle,Skin,Small intestine,Testis,Trachea,
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