Molecular weight (DA)
60kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SNX4. AA range:191-240
Specificity
SNX4 Polyclonal Antibody detects endogenous levels of SNX4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012],
Function
function:May be involved in several stages of intracellular trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,
Protein name
Sorting nexin-4
Other name
SNX4; Sorting nexin-4
Human protein sequence Database
O95219
Mouse protein sequence database
Q91YJ2
Rat protein sequence database
Cellular localization
Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Also detected on a juxtanuclear endocytic recycling compartment (ERC). .
Tissue expression
Liver,Skin,
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