Molecular weight (DA)
62kD
Immunogen
Purified recombinant human GTF2H1protein fragments expressed in E.coli.
Specificity
This antibody detects endogenous levels of GTF2H1 and does not cross-react with related proteins.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
wb 1:300 icc 1:50
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Background
function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,PTM:Phosphorylated.,similarity:Contains 2 BSD domains.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with PUF60.,
Function
function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,PTM:Phosphorylated.,similarity:Contains 2 BSD domains.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with PUF60.,
Other name
Basic transcription factor 2 62 kDa subunit;Basic transcription factor 62 kDa subunit; BTF 2;BTF2;BTF2 p62;General transcription factor IIH polypeptide 1;General transcription factor IIH subunit 1;General transcription factor IIH, polypeptide 1, 62kDa;gtf2h1; TF2H1;TF2H1_HUMAN;TFB1;TFIIH;TFIIH basal transcription factor complex p62 subunit.
Fields
>>Basal transcription factors;>>Nucleotide excision repair;>>Viral carcinogenesis
Human protein sequence Database
P32780
Mouse protein sequence database
Q9DBA9
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Liver,Lung,
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