Molecular weight (DA)
43kD
Immunogen
Synthesized phosho peptide around human FRA1 (Ser265)
Specificity
This antibody detects endogenous levels of Human Mouse Rat FRA1 (phospho-Ser265)
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Function
similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,
Protein name
FRA1 (Ser265)
Other name
Fos-related antigen 1 (FRA-1)
Fields
>>Wnt signaling pathway;>>Osteoclast differentiation;>>IL-17 signaling pathway;>>Human T-cell leukemia virus 1 infection
Human protein sequence Database
P15407
Mouse protein sequence database
P48755
Rat protein sequence database
P10158
Cellular localization
Nucleus .
Tissue expression
Blood,Endothelial cell,Kidney,Skin,
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