Immunogen
Synthesized peptide derived from the Internal region of human CCDC109A.
Specificity
CCDC109A Polyclonal Antibody detects endogenous levels of CCDC109A protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
Function
similarity:Belongs to the CCDC109 family.,
Protein name
Calcium uniporter protein mitochondrial
Other name
MCU; C10orf42; CCDC109A; Calcium uniporter protein; mitochondrial; Coiled-coil domain-containing protein 109A
Fields
>>Calcium signaling pathway;>>Cellular senescence;>>NOD-like receptor signaling pathway;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Spinocerebellar ataxia;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases
Human protein sequence Database
Q8NE86
Mouse protein sequence database
Q3UMR5
Rat protein sequence database
Cellular localization
Mitochondrion inner membrane ; Multi-pass membrane protein .
Tissue expression
Eye,Testis,
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