Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human FOXR1. AA range:231-280
Specificity
FoxR1 Polyclonal Antibody detects endogenous levels of FoxR1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the forkhead box (FOX) family of transcription factors. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 aa. Many FOX transcription factors play roles in determining cell fates during early development. This forkhead box protein lacks the C-terminal basic region found in many other FOX family members. It is located within the 11q23.3 region which is commonly deleted in neuroblastomas. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 fork-head DNA-binding domain.,
Protein name
Forkhead box protein R1
Other name
FOXR1; FOXN5; DLNB13; Forkhead box protein R1; Forkhead box protein N5
Human protein sequence Database
Q6PIV2
Mouse protein sequence database
Q3UTB7
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasm, perinuclear region . Located in the cytoplasm of spermatocytes and strongly accumulates at the perinuclear region in elongated spermatids. .
Tissue expression
Expressed in testis (at protein level).
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