Molecular weight (DA)
44kD
Immunogen
The antiserum was produced against synthesized peptide derived from human LYAR. AA range:241-290
Specificity
LYAR Polyclonal Antibody detects endogenous levels of LYAR protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Contains 2 C2HC-type zinc fingers.,
Function
similarity:Contains 2 C2HC-type zinc fingers.,
Protein name
Cell growth-regulating nucleolar protein
Other name
LYAR; PNAS-5; Cell growth-regulating nucleolar protein
Human protein sequence Database
Q9NX58
Mouse protein sequence database
Q08288
Rat protein sequence database
Cellular localization
Nucleus . Nucleus, nucleolus . Cytoplasm . Cell projection, cilium, photoreceptor outer segment . Component of pre-ribosomal particles, including pre-40S, pre-60S and pre-90S (PubMed:24495227). Associated with cytoplasmic ribosomes, but not polysomes, as a component of the 60S subunit (PubMed:24990247). In the retina, predominantly expressed in photoreceptor outer segments (By similarity). In the nucleolus, colocalizes with nucleolin/NCL, therefore may reside in the dense fibrillar component (DFC) (By similarity). .
Tissue expression
Predominantly expressed in testis.
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