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Med18 Polyclonal Antibody

Polyclonal antibody

Specification

BYab-01862

  • 50UL $180 100UL $255
  • Delivery: In Stock

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Host
Reactiveness
Use
Molecular weight (DA)
24kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MED18. AA range:70-119
Specificity
Med18 Polyclonal Antibody detects endogenous levels of Med18 protein.
Source
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Background
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008],
Function
function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.,similarity:Belongs to the Mediator complex subunit 18 family.,subunit:Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 su
Gene Name
MED18
Protein name
Mediator of RNA polymerase II transcription subunit 18
Abbreviation
Med18
Other name
MED18; Mediator of RNA polymerase II transcription subunit 18; Mediator complex subunit 18; p28b
Fields
Human gene ID
54797
Human protein sequence Database
Q9BUE0
Mouse gene ID
67219
Mouse protein sequence database
Q9CZ82
Rat gene ID
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Colon,Lymphoma,Uterus,
Storage
-20°C/1 year

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Med18 Polyclonal Antibody

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