Molecular weight (DA)
48kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AZI2. AA range:10-59
Specificity
Nap1 Polyclonal Antibody detects endogenous levels of Nap1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008],
Function
function:Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.,subunit:Interacts with IKBKE, TBK1 and TICAM1.,tissue specificity:Widely expressed. Abundant expression seen in the pancreas and testis.,
Protein name
5-azacytidine-induced protein 2
Other name
AZI2; NAP1; 5-azacytidine-induced protein 2; NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP
Fields
>>RIG-I-like receptor signaling pathway
Human protein sequence Database
Q9H6S1
Mouse protein sequence database
Q9QYP6
Rat protein sequence database
Q4KMA0
Cellular localization
Cytoplasm .
Tissue expression
Widely expressed (PubMed:14560022). Abundant expression seen in the pancreas and testis (PubMed:14560022).
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车