Molecular weight (DA)
21kD
Immunogen
The antiserum was produced against synthesized peptide derived from human C1orf57. AA range:141-190
Specificity
NTPase Polyclonal Antibody detects endogenous levels of NTPase protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This gene is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. However, the cytotoxicity is not related to its triphosphatase activity. [provided by RefSeq, Jul 2016],
Function
catalytic activity:NTP + H(2)O = NDP + phosphate.,function:Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency.,similarity:Belongs to the THEP1 NTPase family.,subunit:Monomer.,
Protein name
Cancer-related nucleoside-triphosphatase
Other name
NTPCR; C1orf57; Cancer-related nucleoside-triphosphatase; NTPase; Nucleoside triphosphate phosphohydrolase
Fields
>>Purine metabolism;>>Thiamine metabolism;>>Metabolic pathways;>>Nucleotide metabolism
Human protein sequence Database
Q9BSD7
Mouse protein sequence database
Q9CQA9
Rat protein sequence database
Cellular localization
membrane,extracellular exosome,
Tissue expression
Fetal brain,Skin,
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