Molecular weight (DA)
100kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TF3C2. AA range:71-120
Specificity
TFIIIC110 Polyclonal Antibody detects endogenous levels of TFIIIC110 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.,similarity:Contains 4 WD repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.,
Function
function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.,similarity:Contains 4 WD repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.,
Protein name
General transcription factor 3C polypeptide 2
Other name
GTF3C2; KIAA0011; General transcription factor 3C polypeptide 2; TF3C-beta; Transcription factor IIIC 110 kDa subunit; TFIIIC 110 kDa subunit; TFIIIC110; Transcription factor IIIC subunit beta
Human protein sequence Database
Q8WUA4
Mouse protein sequence database
Q8BL74
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Bone marrow,Brain,Colon,Epithelium,
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