Immunogen
The antiserum was produced against synthesized peptide derived from human TSH1. AA range:851-900
Specificity
TSHZ1 Polyclonal Antibody detects endogenous levels of TSHZ1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012],
Function
function:Transcriptional regulator involved in developmental processes .,similarity:Belongs to the teashirt C2H2-type zinc-finger protein family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 5 C2H2-type zinc fingers.,
Protein name
Teashirt homolog 1
Other name
TSHZ1; SDCCAG33; TSH1; Teashirt homolog 1; Antigen NY-CO-33; Serologically defined colon cancer antigen 33
Human protein sequence Database
Q6ZSZ6
Mouse protein sequence database
Q5DTH5
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.
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