Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from Sox-17 . at AA range: 90-170
Specificity
Sox-17 Polyclonal Antibody detects endogenous levels of Sox-17 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008],
Function
function:Probable transcriptional activator in the premeiotic germ cells. It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum.,
Protein name
Transcription factor SOX-17
Other name
SOX17; Transcription factor SOX-17
Fields
>>Wnt signaling pathway
Human protein sequence Database
Q9H6I2
Mouse protein sequence database
Q61473
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum.