Immunogen
Purified recombinant human ACSM3 (C-terminus) protein fragments expressed in E.coli.
Specificity
ACSM3 Monoclonal Antibody detects endogenous levels of ACSM3 protein.
Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Dilution rate
Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.
Purification process (Immunogen)
Affinity purification
Background
catalytic activity:ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA.,caution:It is uncertain whether Met-1 or Met-9 is the initiator.,cofactor:Magnesium.,function:Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro).,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,
Function
catalytic activity:ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA.,caution:It is uncertain whether Met-1 or Met-9 is the initiator.,cofactor:Magnesium.,function:Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro).,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,
Protein name
Acyl-coenzyme A synthetase ACSM3 mitochondrial
Other name
ACSM3; SAH; Acyl-coenzyme A synthetase ACSM3; mitochondrial; Acyl-CoA synthetase medium-chain family member 3; Butyrate--CoA ligase 3; Butyryl-coenzyme A synthetase 3; Middle-chain acyl-CoA synthetase 3; Protein SA homolog
Fields
>>Butanoate metabolism;>>Metabolic pathways
Human protein sequence Database
Q53FZ2
Mouse protein sequence database
Q3UNX5
Rat protein sequence database
Q6SKG1
Cellular localization
Mitochondrion . Mitochondrion matrix .
Tissue expression
Kidney,Liver,Skin,