Molecular weight (DA)
52kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ALDH3B1. AA range:51-100
Specificity
ALDH3B1 Polyclonal Antibody detects endogenous levels of ALDH3B1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
Function
catalytic activity:An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,tissue specificity:Highest expression in kidney and lung.,
Protein name
Aldehyde dehydrogenase family 3 member B1
Other name
ALDH3B1; ALDH7; Aldehyde dehydrogenase family 3 member B1; Aldehyde dehydrogenase 7
Fields
>>Glycolysis / Gluconeogenesis;>>Histidine metabolism;>>Tyrosine metabolism;>>Phenylalanine metabolism;>>beta-Alanine metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Metabolic pathways
Human protein sequence Database
P43353
Mouse protein sequence database
Q80VQ0
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor . Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.
Tissue expression
Highest expression in kidney and lung.
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