Molecular weight (DA)
53kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 20A1. AA range:191-240
Specificity
CYP20A1 Polyclonal Antibody detects endogenous levels of CYP20A1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
cytochrome P450 family 20 subfamily A member 1(CYP20A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008],
Function
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,
Protein name
Cytochrome P450 20A1
Other name
CYP20A1; Cytochrome P450 20A1
Human protein sequence Database
Q6UW02
Mouse protein sequence database
Q8BKE6
Rat protein sequence database
Cellular localization
Membrane ; Single-pass membrane protein .
Tissue expression
Blood,Lung,Pheochromocytoma,Placenta,Stomach,
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