Molecular weight (DA)
60kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 4F11. AA range:341-390
Specificity
CYP4F11 Polyclonal Antibody detects endogenous levels of CYP4F11 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
cytochrome P450 family 4 subfamily F member 11(CYP4F11) Homo sapiens This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Function
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.,
Protein name
Cytochrome P450 4F11
Other name
CYP4F11; Cytochrome P450 4F11; CYPIVF11
Human protein sequence Database
Q9HBI6
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
Tissue expression
Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.
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