Immunogen
The antiserum was produced against synthesized peptide derived from human ELOVL2. AA range:250-296
Specificity
ELOVL2 Polyclonal Antibody detects endogenous levels of ELOVL2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:Could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
Function
domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:Could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
Protein name
Elongation of very long chain fatty acids protein 2
Other name
ELOVL2; SSC2; Elongation of very long chain fatty acids protein 2; 3-keto acyl-CoA synthase ELOVL2; ELOVL fatty acid elongase 2; ELOVL FA elongase 2
Fields
>>Fatty acid elongation;>>Biosynthesis of unsaturated fatty acids;>>Metabolic pathways;>>Fatty acid metabolism
Human protein sequence Database
Q9NXB9
Mouse protein sequence database
Q9JLJ4
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Liver and testis.
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