Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ELOVL6. AA range:21-70
Specificity
ELOVL6 Polyclonal Antibody detects endogenous levels of ELOVL6 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008],
Function
function:Fatty acid elongase specific to C12-C16 saturated and monoinsaturated fatty acids.,similarity:Belongs to the ELO family.,
Protein name
Elongation of very long chain fatty acids protein 6
Other name
ELOVL6; FACE; LCE; Elongation of very long chain fatty acids protein 6; 3-keto acyl-CoA synthase ELOVL6; ELOVL fatty acid elongase 6; ELOVL FA elongase 6; Fatty acid elongase 2; hELO2; Fatty acyl-CoA elongase; Long-chain fatty-acyl elongase
Fields
>>Fatty acid elongation;>>Biosynthesis of unsaturated fatty acids;>>Metabolic pathways;>>Fatty acid metabolism
Human protein sequence Database
Q9H5J4
Mouse protein sequence database
Q920L5
Rat protein sequence database
Q920L6
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Ubiquitous.
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