Immunogen
The antiserum was produced against synthesized peptide derived from human GPSN2. AA range:259-308
Specificity
GPSN2 Polyclonal Antibody detects endogenous levels of GPSN2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011],
Function
steroid biosynthetic process, steroid metabolic process, lipid biosynthetic process, oxidation reduction,
Protein name
Trans-2,3-enoyl-CoA reductase
Other name
TECR; GPSN2; SC2; Trans-2; 3-enoyl-CoA reductase; TER; Synaptic glycoprotein SC2
Fields
>>Fatty acid elongation;>>Biosynthesis of unsaturated fatty acids;>>Metabolic pathways;>>Fatty acid metabolism
Human protein sequence Database
Q9NZ01
Mouse protein sequence database
Q9CY27
Rat protein sequence database
Q64232
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Expressed in most tissues tested. Highly expressed in skeletal muscle.
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