Molecular weight (DA)
22kD
Immunogen
The antiserum was produced against synthesized peptide derived from human UBE2T. AA range:121-170
Specificity
UBE2T Polyclonal Antibody detects endogenous levels of UBE2T protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene catalyzes the covalent attachment of ubiquitin to protein substrates. Defects in this gene have been associated with Fanconi anemia of complementation group T. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015],
Function
catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,
Protein name
Ubiquitin-conjugating enzyme E2 T
Other name
UBE2T; HSPC150; PIG50; Ubiquitin-conjugating enzyme E2 T; Cell proliferation-inducing gene 50 protein; Ubiquitin carrier protein T; Ubiquitin-protein ligase T
Fields
>>Fanconi anemia pathway
Human protein sequence Database
Q9NPD8
Mouse protein sequence database
Q9CQ37
Rat protein sequence database
Cellular localization
Nucleus . Accumulates to chromatin.
Tissue expression
Adrenal gland,Blood,Carcinoma,Lung,
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