Immunogen
Purified recombinant fragment of human Matrilin-1 expressed in E. Coli.
Specificity
Matrilin-1 Monoclonal Antibody detects endogenous levels of Matrilin-1 protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
Affinity purification
Background
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. [provided by RefSeq, Jul 2008],
Function
function:Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 VWFA domains.,subunit:Homotrimer.,
Protein name
Cartilage matrix protein
Other name
MATN1; CMP; CRTM; Cartilage matrix protein; Matrilin-1
Human protein sequence Database
P21941
Mouse protein sequence database
P51942
Rat protein sequence database
Cellular localization
Secreted, extracellular space, extracellular matrix.
Tissue expression
Muscle,Trachea,