Immunogen
The antiserum was produced against synthesized peptide derived from human DYNLRB2. AA range:21-70
Specificity
Dynein LC 2B Polyclonal Antibody detects endogenous levels of Dynein LC 2B protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.,
Function
function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.,
Protein name
Dynein light chain roadblock-type 2
Abbreviation
Dynein LC 2B
Other name
DYNLRB2; DNCL2B; DNLC2B; ROBLD2; Dynein light chain roadblock-type 2; Dynein light chain 2B; cytoplasmic; Roadblock domain-containing protein 2
Fields
>>Salmonella infection
Human protein sequence Database
Q8TF09
Mouse protein sequence database
Q9DAJ5
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton.
Tissue expression
High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.
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