Molecular weight (DA)
202kD
Immunogen
The antiserum was produced against synthesized peptide derived from human KIF13B. AA range:111-160
Specificity
KIF13B Polyclonal Antibody detects endogenous levels of KIF13B protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May be involved in reorganization of the cortical cytoskeleton. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 CAP-Gly domain.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Binds to DLG1 and DLG4.,tissue specificity:Ubiquitous.,
Function
function:May be involved in reorganization of the cortical cytoskeleton. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 CAP-Gly domain.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Binds to DLG1 and DLG4.,tissue specificity:Ubiquitous.,
Protein name
Kinesin-like protein KIF13B
Other name
KIF13B; GAKIN; KIAA0639; Kinesin-like protein KIF13B; Kinesin-like protein GAKIN
Human protein sequence Database
Q9NQT8
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton . Cell projection, axon . accumulates at the distal part of the microtubules in the tips of axons, but not of dendrites.
Tissue expression
Ubiquitous.
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