Molecular weight (DA)
32kD
Immunogen
The antiserum was produced against synthesized peptide derived from human S100A5. AA range:34-83
Specificity
S-100A5 Polyclonal Antibody detects endogenous levels of S-100A5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
S100 calcium binding protein A5(S100A5) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,
Protein name
Protein S100-A5
Other name
S100A5; S100D; Protein S100-A5; Protein S-100D; S100 calcium-binding protein A5
Human protein sequence Database
P33763
Mouse protein sequence database
P63084
Rat protein sequence database
P63083
Cellular localization
nucleus,neuronal cell body,
Tissue expression
Brain,Kidney,
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