Molecular weight (DA)
25kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PGRMC2. AA range:174-223
Specificity
PGRMC2 Polyclonal Antibody detects endogenous levels of PGRMC2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 137 and 161.,function:Receptor for steroids .,similarity:Belongs to the cytochrome b5 family. MAPR subfamily.,similarity:Contains 1 cytochrome b5 heme-binding domain.,
Function
domain:The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 137 and 161.,function:Receptor for steroids .,similarity:Belongs to the cytochrome b5 family. MAPR subfamily.,similarity:Contains 1 cytochrome b5 heme-binding domain.,
Protein name
Membrane-associated progesterone receptor component 2
Other name
PGRMC2; DG6; PMBP; Membrane-associated progesterone receptor component 2; Progesterone membrane-binding protein; Steroid receptor protein DG6
Human protein sequence Database
O15173
Mouse protein sequence database
Q80UU9
Rat protein sequence database
Q5XIU9
Cellular localization
Membrane ; Single-pass membrane protein . Nucleus envelope . Endoplasmic reticulum .
Tissue expression
Expressed by endometrial glands and stroma (at protein level).
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