Immunogen
Purified recombinant fragment of human AATM expressed in E. Coli.
Specificity
AATM Monoclonal Antibody detects endogenous levels of AATM protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
Affinity purification
Background
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013],
Function
catalytic activity:L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.,cofactor:Pyridoxal phosphate.,function:Facilitates cellular uptake of long-chain free fatty acids.,miscellaneous:In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.,similarity:Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,
Protein name
Aspartate aminotransferase, mitochondrial
Other name
GOT2; Aspartate aminotransferase; mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynu
Fields
>>Arginine biosynthesis;>>Alanine, aspartate and glutamate metabolism;>>Cysteine and methionine metabolism;>>Arginine and proline metabolism;>>Tyrosine metabolism;>>Phenylalanine metabolism;>>Phenylalanine, tyrosine and tryptophan biosynthesis;>>Metabolic pathways;>>Carbon metabolism;>>2-Oxocarboxylic acid metabolism;>>Biosynthesis of amino acids;>>Fat digestion and absorption
Human protein sequence Database
P00505
Mouse protein sequence database
P05202
Rat protein sequence database
P00507
Cellular localization
Mitochondrion matrix . Cell membrane . Exposure to alcohol promotes translocation to the cell membrane. .
Tissue expression
Epithelium,Gastric mucosa,Muscle,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车