Molecular weight (DA)
140kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CEP152. AA range:841-890
Specificity
CEP152 Polyclonal Antibody detects endogenous levels of CEP152 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
centrosomal protein 152(CEP152) Homo sapiens This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010],
Function
sequence caution:Contaminating sequence. Potential poly-A sequence.,
Protein name
Centrosomal protein of 152 kDa
Other name
CEP152; KIAA0912; Centrosomal protein of 152 kDa; Cep152
Human protein sequence Database
O94986
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Colocalizes with CDK5RAP2, WDR62 and CEP63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (PubMed:21983783, PubMed:26297806). Localizes to the deuterosome (By similarity). Localizes to pericentriolar material (PCM) (PubMed:26337392). .
Tissue expression
Bladder,Brain,Heart,Lung,Testis,
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