Immunogen
The antiserum was produced against synthesized peptide derived from human CSTL1. AA range:61-110
Specificity
Cystatin L1 Polyclonal Antibody detects endogenous levels of Cystatin L1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the cystatin family.,
Protein name
Cystatin-like 1
Other name
CSTL1; Cystatin-like 1; RCET11
Human protein sequence Database
Q9H114
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Testis,
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