Molecular weight (DA)
30kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MTIF3. AA range:69-118
Specificity
IF3 Polyclonal Antibody detects endogenous levels of IF3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009],
Function
function:IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.,similarity:Belongs to the IF-3 family.,
Protein name
Translation initiation factor IF-3 mitochondrial
Other name
MTIF3; DC38; Translation initiation factor IF-3; mitochondrial; IF-3(Mt); IF-3Mt; IF3(mt); IF3mt
Human protein sequence Database
Q9H2K0
Mouse protein sequence database
Q9CZD5
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Cervix,Colon,Dendritic cell,Melanocyte,
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