Immunogen
The antiserum was produced against synthesized peptide derived from human MRPS24. AA range:51-100
Specificity
MRP-S24 Polyclonal Antibody detects endogenous levels of MRP-S24 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11. Read-through transcription exists between this gene and the upstream upregulator of cell proliferation (URGCP) gene. [provided by RefSeq, Ma
Function
subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
Protein name
28S ribosomal protein S24 mitochondrial
Other name
MRPS24; HSPC335; 28S ribosomal protein S24; mitochondrial; MRP-S24; S24mt; bMRP-47; bMRP47
Human protein sequence Database
Q96EL2
Mouse protein sequence database
Q9CQV5
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Lung,Umbilical cord blood,
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