Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MRPS30. AA range:390-439
Specificity
MRP-S30 Polyclonal Antibody detects endogenous levels of MRP-S30 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences i
Function
sequence caution:Sequencing errors.,similarity:Belongs to the ribosomal protein S30/L37 family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,tissue specificity:Heart, skeletal muscle, kidney and liver. Lower expression in placenta and peripheral blood leukocytes.,
Protein name
28S ribosomal protein S30 mitochondrial
Other name
MRPS30; PDCD9; BM-047; 28S ribosomal protein S30; mitochondrial; MRP-S30; S30mt; Programmed cell death protein 9
Human protein sequence Database
Q9NP92
Mouse protein sequence database
Q9D0G0
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Heart, skeletal muscle, kidney and liver. Lower expression in placenta and peripheral blood leukocytes.
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