Molecular weight (DA)
28kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PEX11B. AA range:91-140
Specificity
Peroxin 11β Polyclonal Antibody detects endogenous levels of Peroxin 11β protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene facilitates peroxisomal proliferation and interacts with PEX19. The encoded protein is found in the peroxisomal membrane. Several transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012],
Function
caution:PubMed:9792670 states that both the N- and the C-terminus are located in the cytoplasm.,function:Involved in peroxisomal proliferation. May regulate peroxisomes division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane.,similarity:Belongs to the peroxin-11 family.,subunit:Interacts with PEX19.,
Protein name
Peroxisomal membrane protein 11B
Other name
PEX11B; Peroxisomal membrane protein 11B; Peroxin-11B; Peroxisomal biogenesis factor 11B; Protein PEX11 homolog beta; PEX11-beta
Human protein sequence Database
O96011
Mouse protein sequence database
Q9Z210
Rat protein sequence database
Cellular localization
Peroxisome membrane ; Single-pass membrane protein .
Tissue expression
Eye,Liver,