Immunogen
Synthesized peptide derived from PHI-1 . at AA range: 50-130
Specificity
PHI-1 Polyclonal Antibody detects endogenous levels of PHI-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated.,PTM:Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro).,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Ubiquitous. Expressed at low levels.,
Function
function:Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated.,PTM:Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro).,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Ubiquitous. Expressed at low levels.,
Protein name
Protein phosphatase 1 regulatory subunit 14B
Other name
PPP1R14B; PLCB3N; PNG; Protein phosphatase 1 regulatory subunit 14B; Phospholipase C-beta-3 neighbouring gene protein
Human protein sequence Database
Q96C90
Mouse protein sequence database
Q62084
Rat protein sequence database
Q8K3F3
Cellular localization
Cytoplasm .
Tissue expression
Ubiquitous. Expressed at low levels.
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