Immunogen
The antiserum was produced against synthesized peptide derived from human PPP1R1C. AA range:5-54
Specificity
PPP1R1C Polyclonal Antibody detects endogenous levels of PPP1R1C protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010],
Function
function:Inhibitor of protein-phosphatase 1.,similarity:Belongs to the protein phosphatase inhibitor 1 family.,
Protein name
Protein phosphatase 1 regulatory subunit 1C
Other name
PPP1R1C; Protein phosphatase 1 regulatory subunit 1C; Inhibitor-5 of protein phosphatase 1; IPP5
Human protein sequence Database
Q8WVI7
Mouse protein sequence database
Q8BKK4
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Heart,Skeletal muscle,
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