Molecular weight (DA)
26kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PRSS33. AA range:18-67
Specificity
PRSS33 Polyclonal Antibody detects endogenous levels of PRSS33 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Serine protease that has amidolytic activity, cleaving its substrates before Arg residues.,induction:Up-regulated by phorbol ester PMA.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Predominantly expressed in macrophages. Present in the spleen, small and large intestine, lung and brain (at protein level). Highly expressed in peripheral leukocytes, ovary, retina, spleen and stomach. Moderately expressed in thymus, uterus and platelets, as well as some brain tissues, such as thalamus and fetal brain.,
Function
function:Serine protease that has amidolytic activity, cleaving its substrates before Arg residues.,induction:Up-regulated by phorbol ester PMA.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Predominantly expressed in macrophages. Present in the spleen, small and large intestine, lung and brain (at protein level). Highly expressed in peripheral leukocytes, ovary, retina, spleen and stomach. Moderately expressed in thymus, uterus and platelets, as well as some brain tissues, such as thalamus and fetal brain.,
Protein name
Serine protease 33
Other name
PRSS33; Serine protease 33; Serine protease EOS
Human protein sequence Database
Q8NF86
Mouse protein sequence database
Q80WM7
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Predominantly expressed in macrophages. Present in the spleen, small and large intestine, lung and brain (at protein level). Highly expressed in peripheral leukocytes, ovary, retina, spleen and stomach. Moderately expressed in thymus, uterus and platelets, as well as some brain tissues, such as thalamus and fetal brain.